12.5 mg / 5 mL Syrup
H1-RECEPTOR ANTAGONIST
(ANTIHISTAMINE)

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DESCRIPTION OF THE PRODUCT:
Diphenhydramine Hydrochloride (Diplex) 12.5 mg/5 mL is a clear orange syrup with tutti-frutti flavor and sweet fruit taste.

WHAT IS IN THE MEDICINE:
This product contains Diphenhydramine Hydrochloride, an antihistamine, which diminishes or abolishes the main actions of histamine in the body by competitive blockage of histamine receptor sites on tissues; does
not inactivate histamine or prevent its synthesis or release. Histamine H1 receptors are responsible for vasodilation, increased capillary permeability, flare and itch reactions in the skin, and to some extent for contraction of smooth muscle in the bronchi and gastrointestinal tract. A single oral dose of Diphenhydramine Hydrochloride (Diplex) is quickly absorbed, with maximum activity occuring in approximately one hour. The duration of activity following an average dose of Diphenhydramine Hydrochloride (Diplex) is 4 to 6 hours.

STRENGTH OF THE MEDICINE:
Each 5 mL (1 teaspoonful) of syrup contains:
Diphenhydramine Hydrochloride, USP…......................................…12.5 mg

WHAT IS THIS MEDICINE USED FOR?
Used for the symptomatic relief of hypersensitivity reactions and for the control of nausea, vomiting and vertigo of various case.

HOW MUCH AND HOW OFTEN SHOULD YOU USE THIS MEDICINE?
Usual dose for pediatric: 6.25 mg to 25 mg three to four times a day, or a total daily dose of 5 mg/kg body weight in divided doses, up to maximum of 300 mg daily.

WHEN SHOULD YOU NOT TAKE THIS MEDICINE?
Diphenhydramine Hydrochloride (Diplex) is contraindicated in patients with hypersensitivity to Diphenhydramine Hydrochloride and other antihistamines of similar chemical structure; contraindicated to premature infants and newborn; should not be used by treating lower respiratory disease including asthma.