500 mg Capsule
250 mg/5mL Powder for Suspension
100 mg/mL Powder for Suspension (Oral drops)

A N T I B A C T E R I A L

 

FORMULATION:
Each capsule contains:
Cefalexin (as monohydrate), USP…...................………..........……500 mg
Each 5 mL (1 teaspoonful) of reconstituted suspension contains:
Cefalexin (as monohydrate), USP...........................................……250 mg
Each mL of reconstituted oral drops contains:
Cefalexin (as monohydrate), USP.……………...........……........…..100 mg

PHARMACODYNAMICS:
Cefalexin is a semi-synthetic broad spectrum first generation of cephalosporin which exerts its antibacterial activity by binding and inhibiting the action of bacterial cell wall synthesis enzyme. As a result of the interruption of peptidoglycan which lead to weaken bacterial cell and death.

PHARMACOKINETICS:
Cefalexin is acid stable and is almost completely absorbed from the gastrointestinal tract and produces peak plasma concentration 1 hour after administration. Serum concentrations are still detectable after 6 hours. Cefalexin diffuses readily into tissues which include bone, joints, and the pericardial as pleural cavities. Only 10%-15% of the dose is
bound to plasma proteins. The drug crosses into the placenta and small quantity are found in breast milk. The serum half-life of cefalexin is 0.5 to 1.2 hours in adults with normal renal function. The serum half-life of cefalexin in neonates is reported to be about 5 hours and children 3 to 12 months of age is 2.5 hours. Cefalexin is not metabolized in the body.
Elimination is mainly renal with 80% of the dose, excreted from the urine by both glomerular filtration and tubular secretion.

INDICATIONS:
For the treatment of urinary and respiratory tract infections, otitis media, skin and other infections due to sensitive
organisms.

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Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

ADR REPORTING STATEMENT:
For suspected adverse drug reaction, report to the FDA: www.fda.gov.ph
Seek medical attention immediately at the first sign of any adverse drug reaction.

MANUFACTURED FOR:
PRIMERA PHARMA CORP.
#61 C Times St. corner Dalisay St., West Triangle Homes, Quezon CIty

MANUFACTURED BY:
LLOYD LABORATORIES, INC.
No. 10 Lloyd Ave., First Bulacan Industrial City, City of Malolos, Bulacan